• Myeloid sarcoma can be observed

  2019-06-19

  

  Myeloid sarcoma can be observed as a de novo malignancy (without leukemic presentation in peripheral blood and bone marrow), during the course of acute myeloid leukemia (AML), affecting 2.5–9% of all AML patients, myelodysplastic syndromes (MDS) or myeloproliferative neoplasms (MPNs, both chronic my

• Severe ECG abnormality associated with systolic

  2019-06-19

  

  Severe ECG abnormality associated with systolic dysfunction of our DM1 patients. Some degree of electro-mechanical correlation has been demonstrated in several previous studies on DM1 subjects. DM1 patients with prolonged PR or QRS intervals are at four-times higher risk to develop LV systolic dysfu

• br Catheter ablation A reentry

  2019-06-19

  

  Catheter ablation A reentry circuit is supported by complex anatomy and a thick and/or damaged myocardium; thus, high-energy RF application is usually required to create the conduction block line through the critical isthmus of the reentry circuit in patients after ToF repair. A large-tip (8mm) a

• In primary diagnosis IKZF status was not taken into account

  2019-06-18

  

  In primary diagnosis IKZF1 status was not taken into account for risk group stratification. According to protocol ALL-MB-2002 regulations, risk was underestimated and patient was assigned to the SRG. Prognostic value of IKZF1 alterations in ALL, especially BCR-ABL1 negative ALL, is still debated [19

• polo-like kinase 1 Splicing machinery dysfunctions have bee

  2019-06-18

  

  Splicing machinery dysfunctions have been associated to CLL, in particular gene mutations (splicing factor 3B subunit 1) which are present in about 15% of patients . To our knowledge, no gene mutation has ever been detected in CLL. In order to broaden our knowledge on the frequency of splicing mu

• For many decades scientists have warned

  2019-06-18

  

  For many decades, scientists have warned that human activity is pushing life on our planet beyond the point of no return. In the Earth\'s history there have been five mass extinction events, most recently the Cretaceous–Tertiary mass extinction that occurred almost 65 million years ago and was thoug

• br Stephanie Topp points to the limitations of quality measu

  2019-06-18

  

  Stephanie Topp points to the limitations of quality measurement in Commission on High Quality Health Systems (HQSS Commission; May, 2017) that might not fit the real-world contexts of low-income and middle-income countries (LMICs). She also takes issue with a narrow set of generic indicators and

• br The L type calcium channel LTCC

  2019-06-18

  

  The L-type calcium channel (LTCC) in heart consists of 4 subunits: α1, β2, α2, and δ [47], encoded by CACNA1C, CACNB2, and CACNA2D, respectively, with the α2 and δ subunits encoded by the gene CANA2D. In 2007, Antzelevitch et al. [48] reported 2 CACNA1C mutations and a CACNB2 mutation from a genot

• br Conflict of interest br Introduction Far

  2019-06-18

  

  Conflict of interest Introduction Far-field sensing of the atrial electrogram by a ventricular inhibited (VVI) pacemaker is a rare but potentially catastrophic phenomenon if there is no escape rhythm [1–3]. In this setting, the tip of the pacemaker lead is usually located in close proximity to

• br Methods The study protocol was approved

  2019-06-18

  

  Methods The study protocol was approved by the ethics committee at Juntendo University Nerima Hospital. After informed consent was obtained, SBC measurement was performed using a blood sample from each participant. Plasma was separated from each sample immediately after collection by centrifugati

• Most forms of AVNRT are created by reentry between

  2019-06-18

  

  Most forms of AVNRT are created by reentry between two (or more) atrial connections to the AV node. The fast AV nodal pathway (shortest conduction time) is formed by transitional cells crossing the tendon of Todaro superiorly. Two slow AV nodal pathways are formed by the rightward and leftward infer

• No conviene ignorar la enorme influencia cultural

  2019-06-18

  

  No conviene ignorar la enorme influencia cultural de Estados Unidos en la formación intelectual de Vasconcelos, so pena de caer en contradicciones. Ulises criollo se asienta en una tradición muy estadounidense, la de una fascinación por las cuestiones de la individualidad, la identidad y la autobiog

• Este trabajo implic otras formas

  2019-06-18

  

  Este trabajo implicó otras formas de movilidad, fuera simbólica o material. Las armas utilizadas sugieren la capacidad armada y, paradójicamente, los rostros cubiertos ponderan el valor de la clandestinidad, Metoprolol Succinate la vez que rompen con la personificación individual de la lucha, que si

• br Demographic and arrhythmia characteristics gender circadi

  2019-06-17

  

  Demographic and arrhythmia characteristics: gender, circadian pattern of VF, and atrial arrhythmias The prevalence and arrhythmic risk of BS and ERS differ considerably. The BS ECG pattern occurs rarely in the general population, while the ER pattern is a common ECG phenomenon, especially in youn

• Fig D illustrates a long

  2019-06-17

  

  Fig. 4D illustrates a long-lasting and relatively stable rotor with a stationary PS trajectory after perfusion of ryanodine (10μM), which was used to abolish triggered activity in the setting of ACS. Taken together, these results indicate that in the presence of ACS, SRAF is governed by an evolving

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