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Loss of virulence in ACL mutants may be caused by
2023-09-23
Loss of virulence in ACL mutants may be caused by defect in vegetative growth and conidial germination, and reduced trichothecene production. However, supplement of potassium acetate restored the defects in germination rate and vegetative growth, but not virulence in wheat heads (Table 2, Fig. 2B),
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br In vivo visualization of aromatase with positron
2023-09-23
In vivo visualization of aromatase with positron emission tomography (PET) Positron emission tomography (PET) utilizes the high nf-κb inhibitor photons formed during the annihilation of positrons to detect the changes in the amount and localization of injected radiopharmaceuticals in the living
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There are essentially two screening strategies to minimize
2023-09-23
There are essentially two screening strategies to minimize the number of newborns recalled for additional testing without missing cases for most screening disorders. For hyperargininemia, one strategy uses Arg alone as the indicator of possible disease and the other uses Arg in combination with a ra
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The crucial role of AP in establishing and maintaining
2023-09-23
The crucial role of AP-1 in establishing and maintaining cell type-specific gene expression programs and cell identity is further apparent during reprogramming of mouse embryo fibroblasts (MEFs) into iPSCs with either Oct4/Sox2/Klf4/cMyc (OSKM ) factors , or chemicals . Using ATAC-seq to profile ch
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The basis for the protonation of chitosan is the
2023-09-23
The basis for the protonation of chitosan is the alkaline primary amino group, which is also the reason for the special properties of chitosan (Guibal, Van Vooren, Dempsey, & Roussy, 2006; Tamer et al., 2017; Yang et al., 2014). Our previous work (Meng et al., 2012) and several other reports (Yan et
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Betamethasone Dipropionate br Conflict of interest statement
2023-09-23
Conflict of interest statement Introduction Tanshinone IIA (Tan IIA) is a major active component of Salvia miltiorrhiza (S. miltiorrhiza), a well-known Chinese traditional medicine that is used for the treatment of cardiovascular and cerebrovascular diseases [1]. Tan IIA exhibits diverse pharm
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br Funding br Introduction Plants absorb both
2023-09-23
Funding Introduction Plants absorb both inorganic nitrogen (ammonium and nitrate) and organic nitrogen (amino acids and peptides) from the soil [1]. The first organic nitrogenous molecule produced from inorganic nitrogen is Gln, whose terminal amino group is successively transferred to make Gl
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br Materials and methods br Results and discussion
2023-09-23
Materials and methods Results and discussion First, we examined whether hypothalamic Akt-mediated signaling pathways are regulated postprandially in chickens. Refeeding significantly (P orexin concentrations significantly increased in chicks after 1 h of refeeding (958 ± 245% of 24 h-fasting
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CHK has been reported to be the
2023-09-22
CHK1 has been reported to be the kinase responsible for H3.3S31 phosphorylation in human ALT cancer Acarbose . However, in our study, knockdown of CHK1 in HEK293F (Figs. S1c and S6) or HeLa S3 (data not shown) cells did not result in a significant decrease in H3.3S31ph, which is in agreement with a
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br Interaction between ASK and TRX
2023-09-22
Interaction between ASK1 and TRX Thioredoxins are small (∼12kDa) dithiol oxidoreductases ubiquitously expressed in species ranging from plants to archaea and mammals. They perform various biological functions, such as reducing protein disulfide bonds, supplying reducing equivalents to redox apiii
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br Secreted enzymes Only two secreted
2023-09-22
Secreted enzymes Only two secreted S. aureus enzymes reportedly induce apoptosis, namely, staphylococcal staphopain B (SspB) and coagulase. SspB selectively cleaved CD11b/CD18 integrin and induced an apoptosis-like cell death in neutrophils and monocytes (Smagur et al., 2009). Neutrophils or mono
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A Belgian review on perioperative management of drugs recomm
2023-09-22
A Belgian review [9] (2011) on perioperative management of drugs recommends not using ACEI/ARBs due to the same reason. Another 2014 French [10] publication on the management of antihypertensive drugs in the perioperative period suggests withholding this medication before surgery even though they a
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Introduction It has long been recognized that angiogenesis
2023-09-22
Introduction It has long been recognized that angiogenesis is critical to the growth, progression, and metastasis of many solid tumor types [1], and thus, drugs targeting the angiogenic pathway have been a topic of clinical investigation in the oncology community for many years. Angiogenesis is reg
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br Introduction Heart failure HF is a chronically progressiv
2023-09-22
Introduction Heart failure (HF) is a chronically progressive disease and one of the most important causes of morbidity and mortality worldwide despite recent improvements in its treatment [1], [2], [3]. The mortality and morbidity benefits of angiotensin converting enzyme inhibitor (ACEI) are wel
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br Conclusions br Transparency document br Acknowledgements
2023-09-22
Conclusions Transparency document Acknowledgements This work was supported by a grant from the European Commission FP6 “Neuroprion” – Network of Excellence and Royal Veterinary College Bioveterinary science research project funding. We thank Professor Alun Williams (Cambridge University) fo
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