• Our analysis also showed that there were

  2019-04-17

  

  Our analysis also showed that there were no meaningful lipid changes with anastrozle, as a surrogate for cardiovascular health. This is in keeping with the TEAM Japan [17], TEAM Greek [18] sub-studies and the SABRE trial [19], which showed that AIs have no detrimental effects on lipid parameters. Th

• En toda su trayectoria una constante

  2019-04-17

  

  En toda su trayectoria una constante que ha sido reconocida por la comunidad académica y por él mismo, en diversas ocasiones, fue la de “bautizar los nuevos animales”, la de crear conceptos para fenómenos nuevos que consideró específicos, en el marco de la búsqueda en su última etapa de una teoría d

• Cisplatin based chemotherapy is commonly used in adjuvant

  2019-04-16

  

  Cisplatin-based chemotherapy is commonly used in adjuvant CCRT, but data on carboplatin-based chemotherapy with radiotherapy is lacking. Khoury et al reported that patients treated with carboplatin-based chemoradiotherapy show worse outcomes. However, the impact on patient comorbidities was not repo

• br Case report A year old man with a

  2019-04-16

  

  Case report A 56-year-old man with a history of prior myocardial infarction and severe left ventricular dysfunction underwent an implantable cardioverter defibrillator (ICD) bosentan for primary prevention of sudden cardiac death. Since the patient had normal sinus rhythm and normal atrio-ventri

• br Introducci n Las encendidas

  2019-04-16

  

  Introducción Las encendidas palabras de fray Servando Teresa de Mier provienen del Discurso preliminar que acompaña la reedición de la Brevíssima relación de la destruyción de las Indias de fray Bartolomé de las Casas, publicado en México en 1812. Fray Servando no duda en calificar al dominico, l

• De esta manera el trabajo se centra en

  2019-04-16

  

  De esta manera, el trabajo se centra en la discusión sobre las fronteras y territorios en el marco de la globalización y transnacionalización, la configuración de nuevos y viejos espacios simbólicos e identitarios, las interacciones y zonas de contacto existentes entre numerosos conjuntos sociocultu

• br Discussion In this pilot study we report that sequential

  2019-04-16

  

  Discussion In this pilot study, we report that sequential treatment of low dose clofarabine and lenalidomide is safe and feasible for elderly patients with high risk MDS and AML. Only one subject developed dose limiting toxicity (liver dysfunction) from lenalidomide consolidation therapy. Pre-tre

• One of the unheralded developments in global health is the

  2019-04-16

  

  One of the unheralded developments in global health is the welcome increase in the number of older people (ie, aged 60 or 65 years and older) in low-income and middle-income countries. In parallel with the gains from this longevity dividend, ageing presents particular challenges to health services.

• br Conflict of interest br Ethics br Acknowledgment

  2019-04-16

  

  Conflict of interest Ethics Acknowledgment This study was supported by TRF Grants from the Senior Research Scholar Grant, Thailand Research Fund Grant number RTA5580004, and the Higher Education Research Promotion and National Research University Project of Thailand, Office of the Higher Ed

• For example glutamate is increasingly recognized as one of

  2019-04-16

  

  For example, glutamate is increasingly recognized as one of the important dysregulated signaling molecules in cancer biology, especially in the context of bone metastasis. Commonly recognized as an excitatory neurotransmitter necessary for normal proton pump inhibitors function, glutamate is also in

• Furthermore the difference in the

  2019-04-16

  

  Furthermore, the difference in the mean S–A interval between HB capture and non-capture in the 4 patients with conduction pattern 2 or 3 was only 20±4ms (range, 16–27ms), and was shorter than the HV interval after ablation in 3 patients (75%). By contrast, in patients with strictly AV nodal retrogra

• In addition to inducing IKs dysfunction

  2019-04-16

  

  In addition to inducing IKs dysfunction through dominant-negative loss-of-function effects and defective channel trafficking, mutations in KCNQ1 suppress IKs channel function by reducing the channel affinity of interacting proteins [68,69]. Phosphatidylinositol-4,5-bisphosphate (PIP2) is a cofactor

• br Efforts to address malnutrition maternal and

  2019-04-15

  

  Efforts to address malnutrition, maternal and child mortality, and other global health priorities are heavily reliant on behaviour change, including adoption and correct use of health technology, and following treatment recommendations. One long-standing concern is the limited effectiveness of man

• depend br Introduction Cytochrome P CYP plays a

  2019-04-15

  

  Introduction Cytochrome P450 (CYP) plays a key role in drug metabolism. In particular, CYP3A is highly expressed in the human liver and contributes to the metabolism of more than half of current pharmaceutical compounds [1,2]. From the viewpoint of drug-drug interactions, it is important to evalu

• As with any open label study it

  2019-04-15

  

  As with any open-label study, it is possible that a placebo effect may have contributed to patients analgesia after initiation of the therapy. A randomized placebo-controlled trial would be required to finally prove the high analgesic effect of the loading-dose treatment with Ibandronate in metastat

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